That can be useful sometimes, just to have someone check in with them daily.

Sometimes we go so far as to even have directly observed therapy. Or, maybe they need someone to help them at home more. A lot of our patients will get their medications prepackaged, so maybe they need to go into blister packs. So, there's different layers that you can intervene on there. Maybe it's lapses of insurance coverage, or difficulty with having the pharmacy deliver their pills on time, or forgetting. Sometimes it is something that might be fairly easily fixable. When I have patients that have trouble with adherence to medications, I'll start by just trying to ask them, 'What do you think the problem is? What are you having difficulty with? Can you explain to me what happens?' Sometimes patients can articulate, and sometimes they have trouble. I think trying to understand what the barriers for that particular patient are is really the first step, because it's different for everyone. As medication adherence is already a struggle for many patients with HIV for a variety of reasons, what can clinicians do to improve treatment adherence for patients with HIV-associated neurologic disorders? Your presentation highlights a case of toxoplasmosis that recurred after the patient was nonadherent to their treatment plan.

Different barriers patients face can contribute to medication nonadherence in people with HIV, and there are different levels of support available, says Jessica Robinson-Papp, MD, MS, professor of neurology at Icahn School of Medicine at Mt.

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